Attitude Change in Response to an In-Service Teacher Education Programme

How can I tell how successful this course has been? is becoming an increasingly common question in tertiary education. This interest in tertiary teaching and learning is reflected in the fact that one-half of all Australian universities now have tertiary teaching units. There are a number of reasons why evaluation is important. Firstly, discrepancies between the actual and the ideal situation can be detected, causes identified and corrective measures instituted at all stages of the evaluative model, to serve the interests of increased efficiency and improved staff and student satisfaction. Secondly, courses which are continually being evaluated are better able to meet changing demands from students, from the society which the educational institution is serving, and also better able to adjust to internal changes in staff numbers and expertise. Thirdly, evaluation properly conducted can provide a statement of accountability

Exogenously added GPI-anchored tissue inhibitor of matrix metal loproteinase-1 (TIMP-1) displays enhanced and novel biological activities

The family of tissue inhibitors of metalloproteinases (TIMPs) exhibits diverse physiological/biological functions including the inhibition of active matrix metalloproteinases, regulation of proMMP activation, cell growth, and the modulation of angiogenesis. TIMP-1 is a secreted protein that can be detected on the cell surface through its interaction with surface proteins. The diverse biological functions of TIMP-1 are thought to lie, in part, in the kinetics of TIMP-1/MMP/surface protein interactions. Proteins anchored by glycoinositol phospholipids (GPIs), when purified and added to cells in vitro, are incorporated into their surface membranes. A GPI anchor was fused to TIMP-1 to generate a reagent that could be added directly to cell membranes and thus focus defined concentrations of TIMP-1 protein on any cell surface independent of protein-protein interaction. Unlike native TIMP-1, exogenously added GPI-anchored TIMP-1 protein effectively blocked release of MMP-2 and MMP-9 from osteosarcoma cells. TIMP-1-GP1 was a more effective modulator of migration and proliferation than TIMP-1. While control hTIMP-1 protein did not significantly affect migration of primary microvascular endothelial cells at the concentrations tested, the GPI-anchored TIMP-1 protein showed a pronounced suppression of endothelial cell migration in response to bFGF. In addition, TIMP-1-GPI was more effective at inducing microvascular endothelial proliferation. In contrast, fibroblast proliferation was suppressed by the agent. Reagents based on this method should assist in the dissection of the protease cascades and activities involved in TIMP biology. Membrane-fixed TIMP-1 may represent a more effective version of the protein for use in therapeutic expression

Chemical Evolution of Galaxies

Chemical evolution of galaxies brings together ideas on stellar evolution and nucleosynthesis with theories of galaxy formation, star formation and galaxy evolution, with all their associated uncertainties. In a new perspective brought about by the Hubble Deep Field and follow-up investigations of global star formation rates, diffuse background etc., it has become necessary to consider the chemical composition of dark baryonic matter as well as that of visible matter in galaxies.Comment: 6 pages, AAS LaTeX macros v5.0, Millennium Essay to appear in PASP, Feb 200

Dynamic Antarctic ice sheet during the early to mid-Miocene.

Geological data indicate that there were major variations in Antarctic ice sheet volume and extent during the early to mid-Miocene. Simulating such large-scale changes is problematic because of a strong hysteresis effect, which results in stability once the ice sheets have reached continental size. A relatively narrow range of atmospheric CO2 concentrations indicated by proxy records exacerbates this problem. Here, we are able to simulate large-scale variability of the early to mid-Miocene Antarctic ice sheet because of three developments in our modeling approach. (i) We use a climate-ice sheet coupling method utilizing a high-resolution atmospheric component to account for ice sheet-climate feedbacks. (ii) The ice sheet model includes recently proposed mechanisms for retreat into deep subglacial basins caused by ice-cliff failure and ice-shelf hydrofracture. (iii) We account for changes in the oxygen isotopic composition of the ice sheet by using isotope-enabled climate and ice sheet models. We compare our modeling results with ice-proximal records emerging from a sedimentological drill core from the Ross Sea (Andrill-2A) that is presented in a companion article. The variability in Antarctic ice volume that we simulate is equivalent to a seawater oxygen isotope signal of 0.52-0.66‰, or a sea level equivalent change of 30-36 m, for a range of atmospheric CO2 between 280 and 500 ppm and a changing astronomical configuration. This result represents a substantial advance in resolving the long-standing model data conflict of Miocene Antarctic ice sheet and sea level variability

CO\u3csub\u3e2\u3c/sub\u3e and tectonic controls on Antarctic climate and ice-sheet evolution in the mid-Miocene

Antarctic ice sheet and climate evolution during the mid-Miocene has direct relevance for understanding ice sheet (in)stability and the long-term response to elevated atmospheric CO2 in the future. Geologic records reconstruct major fluctuations in the volume and extent of marine and terrestrial ice during the mid-Miocene, revealing a dynamic Antarctic ice-sheet response to past climatic variations. We use an ensemble of climate – ice sheet – vegetation model simulations spanning a range of CO2 concentrations, Transantarctic Mountain uplift scenarios, and glacial/interglacial climatic conditions to identify climate and ice-sheet conditions consistent with Antarctic mid-Miocene terrestrial and marine geological records. We explore climatic variability at both continental and regional scales, focusing specifically on Victoria Land and Wilkes Land Basin regions using a high-resolution nested climate model over these domains. We find that peak warmth during the Miocene Climate Optimum is characterized by a thick terrestrial ice sheet receded from the coastline under high CO2 concentrations. During the Middle Miocene Climate Transition, CO2 episodically dropped below a threshold value for marine-based ice expansion. Comparison of model results with geologic data support ongoing Transantarctic Mountain uplift throughout the mid-Miocene. Modeled ice sheet dynamics over the Wilkes Land Basin were highly sensitive to CO2 concentrations. This work provides a continental-wide context for localized geologic paleoclimate and vegetation records, integrating multiple datasets to reconstruct snapshots of ice sheet and climatic conditions during a pivotal period in Earth\u27s history

Effects of the rainy season on growth of Mimosa tenuiflora in dry tropical forest, Brazil.

Resumo

Uncertainties in the modelled CO2 threshold for Antarctic glaciation

A frequently cited atmospheric CO2 threshold for the onset of Antarctic glaciation of ∼780 ppmv is based on the study of DeConto and Pollard (2003) using an ice sheet model and the GENESIS climate model. Proxy records suggest that atmospheric CO2 concentrations passed through this threshold across the Eocene-Oligocene transition ∼34 Ma. However, atmospheric CO2 concentrations may have been close to this threshold earlier than this transition, which is used by some to suggest the possibility of Antarctic ice sheets during the Eocene. Here we investigate the climate model dependency of the threshold for Antarctic glaciation by performing offline ice sheet model simulations using the climate from 7 different climate models with Eocene boundary conditions (HadCM3L, CCSM3, CESM1.0, GENESIS, FAMOUS, ECHAM5 and GISS-ER). These climate simulations are sourced from a number of independent studies, and as such the boundary conditions, which are poorly constrained during the Eocene, are not identical between simulations. The results of this study suggest that the atmospheric CO2 threshold for Antarctic glaciation is highly dependent on the climate model used and the climate model configuration. A large discrepancy between the climate model and ice sheet model grids for some simulations leads to a strong sensitivity to the lapse rate parameter

Antarctic climate and ice-sheet configuration during the early Pliocene interglacial at 4.23Ma

The geometry of Antarctic ice sheets during warm periods of the geological past is difficult to determine from geological evidence, but is important to know because such reconstructions enable a more complete understanding of how the ice-sheet system responds to changes in climate. Here we investigate how Antarctica evolved under orbital and greenhouse gas conditions representative of an interglacial in the early Pliocene at 4.23Ma, when Southern Hemisphere insolation reached a maximum. Using offline-coupled climate and ice-sheet models, together with a new synthesis of high-latitude palaeoenvironmental proxy data to define a likely climate envelope, we simulate a range of ice-sheet geometries and calculate their likely contribution to sea level. In addition, we use these simulations to investigate the processes by which the West and East Antarctic ice sheets respond to environmental forcings and the timescales over which these behaviours manifest. We conclude that the Antarctic ice sheet contributed 8.6±2.8m to global sea level at this time, under an atmospheric CO2 concentration identical to present (400ppm). Warmer-than-present ocean temperatures led to the collapse of West Antarctica over centuries, whereas higher air temperatures initiated surface melting in parts of East Antarctica that over one to two millennia led to lowering of the ice-sheet surface, flotation of grounded margins in some areas, and retreat of the ice sheet into the Wilkes Subglacial Basin. The results show that regional variations in climate, ice-sheet geometry, and topography produce long-term sea-level contributions that are non-linear with respect to the applied forcings, and which under certain conditions exhibit threshold behaviour associated with behavioural tipping points

Simulating the Antarctic ice sheet in the late-Pliocene warm period: PLISMIP-ANT, an ice-sheet model intercomparison project

In the context of future climate change, understanding the nature and behaviour of ice sheets during warm intervals in Earth history is of fundamental importance. The late Pliocene warm period (also known as the PRISM interval: 3.264 to 3.025 million years before present) can serve as a potential analogue for projected future climates. Although Pliocene ice locations and extents are still poorly constrained, a significant contribution to sea-level rise should be expected from both the Greenland ice sheet and the West and East Antarctic ice sheets based on palaeo sea-level reconstructions. Here, we present results from simulations of the Antarctic ice sheet by means of an international Pliocene Ice Sheet Modeling Intercomparison Project (PLISMIP-ANT). For the experiments, ice-sheet models including the shallow ice and shelf approximations have been used to simulate the complete Antarctic domain (including grounded and floating ice). We compare the performance of six existing numerical ice-sheet models in simulating modern control and Pliocene ice sheets by a suite of five sensitivity experiments. We include an overview of the different ice-sheet models used and how specific model configurations influence the resulting Pliocene Antarctic ice sheet. The six ice-sheet models simulate a comparable present-day ice sheet, considering the models are set up with their own parameter settings. For the Pliocene, the results demonstrate the difficulty of all six models used here to simulate a significant retreat or re-advance of the East Antarctic ice grounding line, which is thought to have happened during the Pliocene for the Wilkes and Aurora basins. The specific sea-level contribution of the Antarctic ice sheet at this point cannot be conclusively determined, whereas improved grounding line physics could be essential for a correct representation of the migration of the grounding-line of the Antarctic ice sheet during the Pliocene